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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCX
All Species:
9.09
Human Site:
S405
Identified Species:
28.57
UniProt:
O43602
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43602
NP_000546.2
441
49318
S405
S
Q
L
S
T
P
K
S
K
Q
S
P
I
S
T
Chimpanzee
Pan troglodytes
XP_529107
435
48278
S399
S
Q
L
S
T
P
K
S
K
Q
S
P
I
S
T
Rhesus Macaque
Macaca mulatta
XP_001100519
441
49265
S405
S
Q
L
S
T
P
K
S
K
Q
S
P
I
S
T
Dog
Lupus familis
XP_853182
417
46576
K382
Q
L
S
T
P
K
S
K
Q
S
P
I
S
T
P
Cat
Felis silvestris
Mouse
Mus musculus
O88809
366
40594
Q331
L
S
T
P
K
S
K
Q
S
P
I
S
T
P
T
Rat
Rattus norvegicus
Q9ESI7
365
40541
K330
Q
L
S
T
P
K
S
K
Q
S
P
I
S
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511397
792
88039
E715
V
N
D
D
G
L
P
E
N
E
H
Q
L
S
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7PLI7
748
82953
K600
G
I
V
H
R
D
I
K
P
E
N
L
L
V
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85
99.3
85.9
N.A.
81.1
81.1
N.A.
36.3
N.A.
N.A.
N.A.
N.A.
22.7
N.A.
N.A.
N.A.
Protein Similarity:
100
87.9
99.5
87.9
N.A.
81.1
81.1
N.A.
43
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
13.3
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
13.3
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
13
0
13
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
13
0
25
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
13
0
0
0
0
0
0
13
0
0
0
0
% H
% Ile:
0
13
0
0
0
0
13
0
0
0
13
25
38
0
0
% I
% Lys:
0
0
0
0
13
25
50
38
38
0
0
0
0
0
13
% K
% Leu:
13
25
38
0
0
13
0
0
0
0
0
13
25
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
0
0
13
0
13
0
0
0
0
% N
% Pro:
0
0
0
13
25
38
13
0
13
13
25
38
0
13
25
% P
% Gln:
25
38
0
0
0
0
0
13
25
38
0
13
0
0
0
% Q
% Arg:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
38
13
25
38
0
13
25
38
13
25
38
13
25
50
0
% S
% Thr:
0
0
13
25
38
0
0
0
0
0
0
0
13
25
50
% T
% Val:
13
0
13
0
0
0
0
0
0
0
0
0
0
13
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _